Wednesday, November 18, 2020

Moderna C19 Vaccine 94.5% Effective

 Pfizer rocked the world last week when it announced a Covid-19 vaccine that had a success rate of 95%.  Moderna followed up with its own Covid-19 vaccine that is just as effective but has less stringent requirements for storage.  The Wall Street Journal reported Monday: 

Moderna Inc. MRNA -4.00% said its experimental coronavirus vaccine was 94.5% effective at protecting people from Covid-19 in an early look at pivotal study results, the second vaccine to hit a key milestone in U.S. testing.

Ninety-five people in a 30,000-subject study developed Covid-19 with symptoms; of those, 90 had received a placebo and only five Moderna’s vaccine.

The findings move the vaccine closer to wide use because they indicate it is effective at preventing disease that causes symptoms, including severe cases. The trial is still under way.

The vaccine also showed signs of being safe, though researchers and regulators must wait for more-complete safety data from the study, expected later in November. Moderna said it plans to ask federal health authorities by early December to clear the vaccine. 

If greenlighted, the shot could go into distribution that month, making it one of the first Covid-19 vaccines to go into distribution in the U.S., where reported coronavirus cases and hospitalizations are surging.

“We may be in a place with a vaccine that has a big impact on the prevention of severe disease,” Moderna Chief Executive Stéphane Bancel said in an interview. “That will be an incredible win against this awful virus.”...

 Moderna’s initial data were reviewed by a committee of independent researchers monitoring the study. The findings provide only a rough snapshot of whether the vaccine works. The company plans to release additional results later, including effectiveness in specific groups such as the elderly and against infections that don’t produce symptoms.

 Moderna’s vaccine, like Pfizer’s, uses a new technology known as messenger RNA. It works by delivering genetic instructions that teach human cells to make a protein resembling one found on the surface of the coronavirus. That triggers an immune response designed to protect vaccinated people if they are later exposed to the actual virus...

 The logistics of getting both vaccines into the arms of people could be challenging because it will require the shots to be kept at a range of cold temperatures. Moderna’s vaccine must be shipped and kept in long-term storage at a below-freezing temperature equal to most home or medical freezer temperatures. Moderna said Monday it now expects its vaccine, after thawing, can remain stable in regular refrigerator storage for up to 30 days—longer than its previous estimate of seven days. Pfizer’s vaccine must be stored at even colder temperatures and then can be kept at standard refrigeration temperatures for about five days....

The FDA wants to see two months of safety monitoring for at least half of the 30,000 people in the trial, a milestone Moderna expects by the end of November. In the early look, the company said no significant safety concerns were reported, and the vaccine was generally well tolerated, with injection-site pain for some people after the first dose, and fatigue, headache and joint pain after the second.

If regulators do authorize the vaccine, the initial supply of doses will be limited—20 million, or enough for 10 million people, by the end of the year, Moderna forecasts. If the Pfizer vaccine is also authorized, federal officials said Monday they expect to be able to immunize about 20 million Americans during December.... Rest of article. 


25 comments:

Anonymous said...

Saw today where Pfizer has now met the requirements for requesting emergency use authorization and will do so in a few days. FDA has blocked off December 8-10 for meetings, presumably to consider this request and Moderna's if they also hit their threshold of positive cases.

Don't let this give you false confidence though. Even under the best of circumstances a mid-December vaccination will be useless against spreading the virus at Thanksgiving and Christmas gatherings. Until the vaccine is widely distributed we will see COVID cases and deaths continue and likely increase over the next few months. It will be the end of March at the earliest before vaccination results will show up in decreasing case counts, and more importantly in the death count.

We're closer, but ultimately we are not going to be any better off for a while yet.

Anonymous said...

false confidence? how about ticker tape parades. This is a big deal.

Anonymous said...

94% effective on a cold over 99% of the population recovers from.

Anonymous said...

Actually Pfizer first reported last week that it's vaccine was 90% effective, and then Moderna came out earlier this week and said its was 94.5% effective. Not to be outdone, Pfizer came out yesterday and said its is now actually 95% effective.

(I wonder how Pfizer's rate increased 5% with no more testing done in the last few days. And I supposed Moderna will say tomorrow its is 96%, then Pfizer will say a day later its is 97%, etc...)

Anonymous said...

This is good news. No mention of how long it takes for the vaccine to be effective. For example, the flu vaccine takes 2 weeks to kick in.

Anonymous said...

Admonitions and cautions from anonymous expert @ 2:34. LMAO Get.Over.Yourself.

Anonymous said...

2:59. yes the cold that has killed over 255 thousand in our country, and 1.3 million around the world...

Anonymous said...

We will be in the first public line to get the vaccine. However, if you combine all of the doses of vaccine said to be available (Pfizer and Moderna combined) there is still not sufficient vaccine to vaccinate all health care workers, and IMO, they need to come first, followed by first responders, police, firefighters and perhaps the military. It will likely be sometime in the first quarter before there are any publicly available vaccines for general distribution. IMO, that is the way it should be, and Both the wife and I are in the highest risk groups (Age and heart/respiratory risk).

Regarding Pfizer, their vaccine must be stored at very low temperature and there are very few medical freezing units that will run that low. The company that makes them has 50 employees and says there is no way they can produce the units needed. Moderna has a much more friendly storage temperature requirement and will be more user friendly when shipped and stored. Both vaccines have at least a week long refrigerated storage Lifespan. I can assure you, a vial of vaccine will not last anywhere close to a week, once thawed, since each vial likely will only do less than ten vaccines. I see then thawing them and using the vial in an hour or two. It will eventually get to the point where they tell the public, "We are thawing ten vials tomorrow, so get in line early, or wait until the next day to come get your shot" - or "you must arrange to get vaccinated by appointment only!"

Once they get enough vaccine, they need to vaccinate the way we got vaccinated in the Army. You would line up and march between two guys who had high pressure "guns" that would shoot the vaccine through your skin without a needle. Then they would march you ten miles to work the soreness out of your arms. The only needle shot I can remember ever getting was the plague vaccine.

Anonymous said...

3:04

They had to wait until they got a certain number of cases. One those cases came in, the percentage would either go higher or lower. It went higher.

Anonymous said...

3:04

Obviously Pfizer uses the Dominion software.

Anonymous said...

Now it’s just a game of avoiding the maskless covidiots until the 7.8 billion doses needed to inoculate every human on the planet are widely available. Hopefully the covidiots and anti-vaxxers will pass on it, leaving more the rest of us.

Anonymous said...

"94% effective on a cold over 99% of the population recovers from." Thank you for that post. I agree. Shame they have people so fucking panicked over this. For those salivating at the prospect of this so called we will save the world vaccine, remember the movie "I am Legend" and how that ended.

Anonymous said...

This is great news. Covid is the third leading cause of death in the US for 2020.

Anonymous said...

Once I take one of these vaccines, I am still going to wear a mask. "Don't Thread on Me"

Anonymous said...

Hey anonymous expert @3:14, care to refute anything in the original post at 2:34 or are you just another COVID denier?

Anonymous said...

Vaccines do not work! They kill and maim babies!

My body my choice.

And masks? Bunch of libtards.

Walk it off ya snatches.

Anonymous said...

@3:21, ive got a MUCH better idea about how “we” should get vaccinated. YOU give me a shot if you get past my first “shot”@3:44

Anonymous said...

The troll force is strong today.

Anonymous said...

Here is a great short article about what the military is doing:

https://www.nytimes.com/interactive/2020/11/16/us/virus-military.html?action=click&module=News&pgtype=Homepage

I think the most interesting points: quarantine to weed out unsuitable candidates and the fact that they want to continue many measures even beyond Covid....

Calm Down said...

I don't think the line for the first vaccination will be very crowded.

Jacksun said...

Dead last in priority to receive the vaccine should be 5:21 and the other loud covid deniers. They think C19 is no big deal? Fine, let others receive the vaccine well before they do. And if they get a bad case of C19 in the meantime? Well that's Karma baby!

Anonymous said...

Does the injection contain a microchip or not?

Anonymous said...

Actually 5:21 should be one of the first to receive the vaccine. Such a lack of caring on their part means they are one of the most likely to be spreading the virus. I don't care one bit if they get sick or not, but preventing them from being able to deliberately jeopardizing innocent people is more important.

Anonymous said...

November 18, 2020 at 3:16 PM
One word: Comorbidities

Jacksun said...

1:40pm: There are plenty of young people without comorbidities who have developed long term Covid complications, some become long haulers, some of whom even died. The virus is very unpredictable, and the exceptions prove the rule that this is a dangerous virus. Don't deny the power of nature. It is stronger than you. Respect nature; respect science; respect each other; and quit listening to that quack Scot Atlas or Fox News, OAN, NewsWatch, Donald Trump and other lying propogandists who have politicized a dangerous virus and brainwashed people into thinking the virus is the flu.



Recent Comments

Search Jackson Jambalaya

Subscribe to JJ's Youtube channel

Archives

Trollfest '09

Trollfest '07 was such a success that Jackson Jambalaya will once again host Trollfest '09. Catch this great event which will leave NE Jackson & Fondren in flames. Othor Cain and his band, The Black Power Structure headline the night while Sonjay Poontang returns for an encore performance. Former Frank Melton bodyguard Marcus Wright makes his premier appearance at Trollfest singing "I'm a Sweet Transvestite" from "The Rocky Horror Picture Show." Kamikaze will sing his new hit, “How I sold out to da Man.” Robbie Bell again performs: “Mamas, don't let your babies grow up to be Bells” and “Any friend of Ed Peters is a friend of mine”. After the show, Ms. Bell will autograph copies of her mug shot photos. In a salute to “Dancing with the Stars”, Ms. Bell and Hinds County District Attorney Robert Smith will dance the Wango Tango.

Wrestling returns, except this time it will be a Battle Royal with Othor Cain, Ben Allen, Kim Wade, Haley Fisackerly, Alan Lange, and “Big Cat” Donna Ladd all in the ring at the same time. The Battle Royal will be in a steel cage, no time limit, no referee, and the losers must leave town. Marshand Crisler will be the honorary referee (as it gives him a title without actually having to do anything).


Meet KIM Waaaaaade at the Entergy Tent. For five pesos, Kim will sell you a chance to win a deed to a crack house on Ridgeway Street stuffed in the Howard Industries pinata. Don't worry if the pinata is beaten to shreds, as Mr. Wade has Jose, Emmanuel, and Carlos, all illegal immigrants, available as replacements for the it. Upon leaving the Entergy tent, fig leaves will be available in case Entergy literally takes everything you have as part of its Trollfest ticket price adjustment charge.

Donna Ladd of The Jackson Free Press will give several classes on learning how to write. Smearing, writing without factchecking, and reporting only one side of a story will be covered. A donation to pay their taxes will be accepted and she will be signing copies of their former federal tax liens. Ms. Ladd will give a dramatic reading of her two award-winning essays (They received The Jackson Free Press "Best Of" awards.) "Why everything is always about me" and "Why I cover murders better than anyone else in Jackson".

In the spirit of helping those who are less fortunate, Trollfest '09 adopts a cause for which a portion of the proceeds and donations will be donated: Keeping Frank Melton in his home. The “Keep Frank Melton From Being Homeless” booth will sell chances for five dollars to pin the tail on the jackass. John Reeves has graciously volunteered to be the jackass for this honorable excursion into saving Frank's ass. What's an ass between two friends after all? If Mr. Reeves is unable to um, perform, Speaker Billy McCoy has also volunteered as when the word “jackass” was mentioned he immediately ran as fast as he could to sign up.


In order to help clean up the legal profession, Adam Kilgore of the Mississippi Bar will be giving away free, round-trip plane tickets to the North Pole where they keep their bar complaint forms (which are NOT available online). If you don't want to go to the North Pole, you can enjoy Brant Brantley's (of the Mississippi Commission on Judicial Performance) free guided tours of the quicksand field over by High Street where all complaints against judges disappear. If for some reason you are unable to control yourself, never fear; Judge Houston Patton will operate his jail where no lawyers are needed or allowed as you just sit there for minutes... hours.... months...years until he decides he is tired of you sitting in his jail. Do not think Judge Patton is a bad judge however as he plans to serve free Mad Dog 20/20 to all inmates.

Trollfest '09 is a pet-friendly event as well. Feel free to bring your dog with you and do not worry if your pet gets hungry, as employees of the Jackson Zoo will be on hand to provide some of their animals as food when it gets to be feeding time for your little loved one.

Relax at the Fox News Tent. Since there are only three blonde reporters in Jackson (being blonde is a requirement for working at Fox News), Megan and Kathryn from WAPT and Wendy from WLBT will be on loan to Fox. To gain admittance to the VIP section, bring either your Republican Party ID card or a Rebel Flag. Bringing both and a torn-up Obama yard sign will entitle you to free drinks served by Megan, Wendy, and Kathryn. Get your tickets now. Since this is an event for trolls, no ID is required. Just bring the hate. Bring the family, Trollfest '09 is for EVERYONE!!!

This is definitely a Beaver production.


Note: Security provided by INS.

Trollfest '07

Jackson Jambalaya is the home of Trollfest '07. Catch this great event which promises to leave NE Jackson & Fondren in flames. Sonjay Poontang and his band headline the night with a special steel cage, no time limit "loser must leave town" bout between Alan Lange and "Big Cat"Donna Ladd following afterwards. Kamikaze will perform his new song F*** Bush, he's still a _____. Did I mention there was no referee? Dr. Heddy Matthias and Lori Gregory will face off in the undercard dueling with dangling participles and other um, devices. Robbie Bell will perform Her two latest songs: My Best Friends are in the Media and Mama's, Don't Let Your Babies Grow up to be George Bell. Sid Salter of The Clarion-Ledger will host "Pin the Tail on the Trial Lawyer", sponsored by State Farm.

There will be a hugging booth where in exchange for your young son, Frank Melton will give you a loooong hug. Trollfest will have a dunking booth where Muhammed the terrorist will curse you to Allah as you try to hit a target that will drop him into a vat of pig grease. However, in the true spirit of Separate But Equal, Don Imus and someone from NE Jackson will also sit in the dunking booth for an equal amount of time. Tom Head will give a reading for two hours on why he can't figure out who the hell he is. Cliff Cargill will give lessons with his .80 caliber desert eagle, using Frank Melton photos as targets. Tackleberry will be on hand for an autograph session. KIM Waaaaaade will be passing out free titles and deeds to crackhouses formerly owned by The Wood Street Players.

If you get tired come relax at the Fox News Tent. To gain admittance to the VIP section, bring either your Republican Party ID card or a Rebel Flag. Bringing both will entitle you to free drinks.Get your tickets now. Since this is an event for trolls, no ID is required, just bring the hate. Bring the family, Trollfest '07 is for EVERYONE!!!

This is definitely a Beaver production.

Note: Security provided by INS
.