Sunday, September 23, 2018

Ole Miss Can't Grow Enough Weed

It appears Ole Miss is losing it's monopoly on legally growing marijuana.  The Associated Press reported last week:


In a rare move, the U.S. government has approved the importation of marijuana extracts from Canada for a clinical trial, highlighting a new avenue for American researchers who have long had trouble obtaining the drug for medical studies.

The University of California San Diego’s Center for Medicinal Cannabis Research announced Tuesday the Drug Enforcement Administration has OK’d its plans to import capsules containing two key cannabis compounds — CBD and THC — from British Columbia-based Tilray Inc . to study their effectiveness in treating tremors that afflict millions of people, especially those over 65.

Marijuana remains illegal under federal law, making it impossible for researchers to simply obtain forms of the drug from one of the many medical marijuana programs approved by individual states — even a state with a pot culture as prevalent as California’s.

Instead, federal law dictates that researchers typically must obtain any weed for clinical trials through the National Institute on Drug Abuse, which uses cannabis grown at the University of Mississippi. Scientists have long complained about the difficulty of obtaining that marijuana, as well as its limited quality, variety and usefulness for clinical research.

The University of California San Diego researchers said they needed marijuana extracts in capsule form because it’s easier to monitor the doses that patients receive, compared to having patients smoke or vaporize it. They also believed many older patients would be reluctant to participate in the study if they had to inhale the drug, according to Dr. Fatta Nahab, a UCSD neurologist and the tremor study’s principal investigator.

NIDA doesn’t offer capsules, so the researchers spent about two years going through regulatory hoops to obtain permission to import the drug from Canada, where medical marijuana is federally legal and where recreational sales begin nationwide next month.

Paul Armentano, deputy director of the marijuana law reform organization NORML, said that illustrates how badly American researchers need alternative sources for cannabis. The House Judiciary Committee last week passed a bill to require the Justice Department to issue at least two more licenses to U.S. facilities to grow pot for research.

“It’s very telling that you have researchers in the U.S. willing to exert the patience and go through the regulatory hurdles to make this happen at the same time the United States has its own domestic supply source,” Armentano said.

Marijuana compounds have been imported for clinical trials before, including by Britain-based GW Pharmaceuticals, which won approval this year to sell its purified CBD capsule, Epidiolex, to treat severe forms of epilepsy — the first cannabis drug approved by the U.S. Food and Drug Administration. While GW Pharmaceuticals developed that drug in-house before bringing it to the U.S. for testing, Tilray, which recently became the first marijuana company to complete an initial public stock offering in the U.S., said it can work with researchers to develop the cannabis formulations they hope to study.

“It’s a really big milestone for Tilray and also just for the whole industry,” said Catherine Jacobson, Tilray’s director of clinical research. “Researchers in the U.S. have really been limited to doing research using dried flower. We have been able to prove to the FDA that we can manufacture investigational study drugs containing cannabinoids that meet their standards.”....

NIDA intends to expand how much marijuana the University of Mississippi grows for research. The agency’s contract with the university provides for the possibility of offering cannabis capsules, but it has not yet done so, said Don Stanford, assistant director of the Research Institute of Pharmaceutical Sciences at the university.

There is no drug designed to treat essential tremor, a shaking condition. Unlike Parkinson’s disease, which causes shaking when someone is not moving, people with essential tremors shake when they are, making everyday activities like writing, drinking and speaking difficult. The condition afflicts 10 million people nationally and millions more across the globe, according to the International Essential Tremor Foundation.

Many patients try to control the shaking by repurposing other drugs, such as blood pressure medicine, with limited success.

Nahab said he started looking into whether marijuana could be used to treat essential tremor after two patients showed sudden improvement after smoking pot or consuming CBD purchased online.

The FDA application outlined the drug formula — a 20:1 ratio of CBD to THC, to minimize any high study participants might feel — as well as its purity, toxicity, shelf life and other details. Researchers also had to get safety approvals from the university and present their plans to a California research advisory panel.

The university hopes to have 16 to 20 patients in the study, which will begin early next year. Researchers will monitor the tremors with a device placed on the wrist and record changes in the severity of the shaking.

Tilray is providing the drug and limited financial support but said it will have no role in reviewing the study’s results.

“Essential tremor is 10 times more common than Parkinson’s and yet nobody really knows about essential tremor,” Nahab said. “That we’re finally getting to a potential therapeutic option in an area that is untapped is a big deal.” Rest of article.

Kingfish note:  Meanwhile, Instagram King Dan Bilzerian, yes, that Dan Bilzerian, launched his own high-quality line of CBD oil products.  Posted below is the video of the launch party.



All kidding aside, the ban on research is dumb.  Marijuana is a plant.  Just because it can be misused doesn't mean it doesn't have any value on the medical side of things.  There is nothing unethical or immoral about studying its medical uses in a research laboratory.  

21 comments:

Anonymous said...

So the Trent Lott institute of pot cannot produce pot. Another one of his pet projects that fail, because there was no good reason for the National Institute to be placed at UM in the first place.

The only pot that Trent could justify at his alma mater, would be the pot for him to cook his pork fat in - again.

Anonymous said...

Not enough, just really poor quality, they are growing much better stuff in Madison and Rankin.

Anonymous said...

@557, don't leave out Jeff Davis county! They grow enough in one spot to take care of the Madison market. (Used to be covered from the north in Leake County until they busted up that large plantation a few years ago.)

And their stuff is supposed to be top notch. Might it be that the best of the Trent Lott material is used to take care of the hookers and thugs on the square Saturday nights, leaving only the poorer quality for the feds?

Anonymous said...

Could have been at the forefront, instead.....oh..$#...

Anonymous said...

@5:57

I don’t know what you’re talking about. I grow mine in Lincoln county, and it’s top notch.

Anonymous said...

*its

Anonymous said...

Wrong, it’s “it’s.” The pot grower was correct after all.

Anonymous said...

The leg humpers could have used a little something to loosen them up last night in the blue grass state. They were a bit tense and sensitive.

Anonymous said...

After legal Sport Betting & Lottery passed in our fine state legalizing marijuana will be Next. Tote that Duebee, Hammer the roach.

Anonymous said...

Why can't they make it in pill form?

It would preserve the monopoly.

Course, will Cindy Lou-who fight to retain the monopoly and the jobs at Ole Miss, or allow them to go out-of-state?

Anonymous said...

Where can I get this stuff (for research only)? Will settle for low grade. Axing for a friend.

Anonymous said...

I don't think this was Trent Lott's pork. The pot farm goes back to Jamie Whitten.

Anonymous said...

11:04 they already do, I think that's what they are importing...

Anonymous said...

The pot farm was at Ole Miss long before anybody heard of Trent Lott. But don't let that get in the way of changing the subject

Anonymous said...

Long before anybody heard of Trent Lott? Hell, back in 1971 Ole Miss, like many other college campuses weren't interested in pot, they were into hard drugs.

Realize you might not have heard of Lott until he held his bro-in-laws wallet while he screwed the country out of billions, but Lott thought a lot of himself long before that.

Anonymous said...

Lott was a cheerleader at OM before the pot farm. Cochran too.

Be smart! Not greedy! said...

To grow good pot, start in small flower pots, indoors. Then move to five gallon buckets (with vegetable miracle gro), at this point you can place them in a young pine thicket. Once they reach 3-4 feet tall, place them into a large hole, filled with miracle grow. Wrap strong fishing line around the perimeter, as deer love to eat marijuana plants. Plant no more than three plants in an area, to prevent being detected from above. Once the plants are outside and in the ground, do not tend to them more than once a month. Therefore it’s best to plant before several days of rain. Majority of people are caught because they tend the plants too often. A key piece of equipment is wireless game cameras, that send pictures directly to a burner phone. If you get pictures of people looking at your plants, don’t go back.

Anonymous said...

Dude!

Anonymous said...

Can someone help me out, my brother in law is a cop and he hunts our family land.

Anonymous said...

@6:14

The State is full of land owned by senior citizens and by timber companies, neither of which do much more than ride the firelanes once a year, if that. Just trespass, if the plants are the right age when you plant them, you will only go on site a few times. Even if it’s land that is used, no one ventures into a pine thicket of 4-8 year old trees unless it is to clear firelanes. Just don’t leave a trail. Careful not to break branches, knock down thickets, etc. Or just tell your in law that it isn’t his land and to not come out anymore. Also, another thing to consider, is if your brother in law is a regular cop then more than likely he is a complete dumbass.

Anonymous said...

there are lots of option nowadays like this one https://www.gyo.green/cannabis-seedbanks/ace-seeds-cannabis-seeds

Suscribe to latest on JJ.

Recent Comments

Search Jackson Jambalaya

Subscribe to JJ's Youtube channel

Archives

Trollfest '09

Trollfest '07 was such a success that Jackson Jambalaya will once again host Trollfest '09. Catch this great event which will leave NE Jackson & Fondren in flames. Othor Cain and his band, The Black Power Structure headline the night while Sonjay Poontang returns for an encore performance. Former Frank Melton bodyguard Marcus Wright makes his premier appearance at Trollfest singing "I'm a Sweet Transvestite" from "The Rocky Horror Picture Show." Kamikaze will sing his new hit, “How I sold out to da Man.” Robbie Bell again performs: “Mamas, don't let your babies grow up to be Bells” and “Any friend of Ed Peters is a friend of mine”. After the show, Ms. Bell will autograph copies of her mug shot photos. In a salute to “Dancing with the Stars”, Ms. Bell and Hinds County District Attorney Robert Smith will dance the Wango Tango.

Wrestling returns, except this time it will be a Battle Royal with Othor Cain, Ben Allen, Kim Wade, Haley Fisackerly, Alan Lange, and “Big Cat” Donna Ladd all in the ring at the same time. The Battle Royal will be in a steel cage, no time limit, no referee, and the losers must leave town. Marshand Crisler will be the honorary referee (as it gives him a title without actually having to do anything).


Meet KIM Waaaaaade at the Entergy Tent. For five pesos, Kim will sell you a chance to win a deed to a crack house on Ridgeway Street stuffed in the Howard Industries pinata. Don't worry if the pinata is beaten to shreds, as Mr. Wade has Jose, Emmanuel, and Carlos, all illegal immigrants, available as replacements for the it. Upon leaving the Entergy tent, fig leaves will be available in case Entergy literally takes everything you have as part of its Trollfest ticket price adjustment charge.

Donna Ladd of The Jackson Free Press will give several classes on learning how to write. Smearing, writing without factchecking, and reporting only one side of a story will be covered. A donation to pay their taxes will be accepted and she will be signing copies of their former federal tax liens. Ms. Ladd will give a dramatic reading of her two award-winning essays (They received The Jackson Free Press "Best Of" awards.) "Why everything is always about me" and "Why I cover murders better than anyone else in Jackson".

In the spirit of helping those who are less fortunate, Trollfest '09 adopts a cause for which a portion of the proceeds and donations will be donated: Keeping Frank Melton in his home. The “Keep Frank Melton From Being Homeless” booth will sell chances for five dollars to pin the tail on the jackass. John Reeves has graciously volunteered to be the jackass for this honorable excursion into saving Frank's ass. What's an ass between two friends after all? If Mr. Reeves is unable to um, perform, Speaker Billy McCoy has also volunteered as when the word “jackass” was mentioned he immediately ran as fast as he could to sign up.


In order to help clean up the legal profession, Adam Kilgore of the Mississippi Bar will be giving away free, round-trip plane tickets to the North Pole where they keep their bar complaint forms (which are NOT available online). If you don't want to go to the North Pole, you can enjoy Brant Brantley's (of the Mississippi Commission on Judicial Performance) free guided tours of the quicksand field over by High Street where all complaints against judges disappear. If for some reason you are unable to control yourself, never fear; Judge Houston Patton will operate his jail where no lawyers are needed or allowed as you just sit there for minutes... hours.... months...years until he decides he is tired of you sitting in his jail. Do not think Judge Patton is a bad judge however as he plans to serve free Mad Dog 20/20 to all inmates.

Trollfest '09 is a pet-friendly event as well. Feel free to bring your dog with you and do not worry if your pet gets hungry, as employees of the Jackson Zoo will be on hand to provide some of their animals as food when it gets to be feeding time for your little loved one.

Relax at the Fox News Tent. Since there are only three blonde reporters in Jackson (being blonde is a requirement for working at Fox News), Megan and Kathryn from WAPT and Wendy from WLBT will be on loan to Fox. To gain admittance to the VIP section, bring either your Republican Party ID card or a Rebel Flag. Bringing both and a torn-up Obama yard sign will entitle you to free drinks served by Megan, Wendy, and Kathryn. Get your tickets now. Since this is an event for trolls, no ID is required. Just bring the hate. Bring the family, Trollfest '09 is for EVERYONE!!!

This is definitely a Beaver production.


Note: Security provided by INS.

Trollfest '07

Jackson Jambalaya is the home of Trollfest '07. Catch this great event which promises to leave NE Jackson & Fondren in flames. Sonjay Poontang and his band headline the night with a special steel cage, no time limit "loser must leave town" bout between Alan Lange and "Big Cat"Donna Ladd following afterwards. Kamikaze will perform his new song F*** Bush, he's still a _____. Did I mention there was no referee? Dr. Heddy Matthias and Lori Gregory will face off in the undercard dueling with dangling participles and other um, devices. Robbie Bell will perform Her two latest songs: My Best Friends are in the Media and Mama's, Don't Let Your Babies Grow up to be George Bell. Sid Salter of The Clarion-Ledger will host "Pin the Tail on the Trial Lawyer", sponsored by State Farm.

There will be a hugging booth where in exchange for your young son, Frank Melton will give you a loooong hug. Trollfest will have a dunking booth where Muhammed the terrorist will curse you to Allah as you try to hit a target that will drop him into a vat of pig grease. However, in the true spirit of Separate But Equal, Don Imus and someone from NE Jackson will also sit in the dunking booth for an equal amount of time. Tom Head will give a reading for two hours on why he can't figure out who the hell he is. Cliff Cargill will give lessons with his .80 caliber desert eagle, using Frank Melton photos as targets. Tackleberry will be on hand for an autograph session. KIM Waaaaaade will be passing out free titles and deeds to crackhouses formerly owned by The Wood Street Players.

If you get tired come relax at the Fox News Tent. To gain admittance to the VIP section, bring either your Republican Party ID card or a Rebel Flag. Bringing both will entitle you to free drinks.Get your tickets now. Since this is an event for trolls, no ID is required, just bring the hate. Bring the family, Trollfest '07 is for EVERYONE!!!

This is definitely a Beaver production.

Note: Security provided by INS
.